Herpatch Cold Sore Treatment Serum - Treat & Prevent Coldsores - Cold Sore Cream Alternative - Heals in 24 Hrs - Relieves Pain, Reduce Swelling & Blistering - Clinically Proven - inc SPF 30 Lip Balm.

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Herpatch Cold Sore Treatment Serum - Treat & Prevent Coldsores - Cold Sore Cream Alternative - Heals in 24 Hrs - Relieves Pain, Reduce Swelling & Blistering - Clinically Proven - inc SPF 30 Lip Balm.

Herpatch Cold Sore Treatment Serum - Treat & Prevent Coldsores - Cold Sore Cream Alternative - Heals in 24 Hrs - Relieves Pain, Reduce Swelling & Blistering - Clinically Proven - inc SPF 30 Lip Balm.

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Raborn, G. W. & Grace, M. G. Recurrent herpes simplex labialis: selected therapeutic options. J. Can. Dent. Assoc. 69, 498–503 (2003).

Ne nazadnje pa cinkov sulfat zmanjša bolečino in srbečico, njegovo delovanje je tudi adstringentno, tako da kožo utrdi, okrepi in poveča njeno prožnost. Cinkov sulfat s tem pospeši celjenje kože na predelih s herpesom. The statistical analysis of the reaction rate and the reaction quality showed statistically significant differences between Herpatch and Compeed as well as between Herpatch and Zovirax, both in favour of Herpatch. Karlsmark et al. evaluated the same parameters without assessing statistically significant differences between Compeed and Zovirax 22. Hydrocolloid wound dressings such as the Compeed patches promote re-epithelialization and reduce inflammatory responses 41, 42. However, in this clinical trial, the patch had to be removed several times due to the patch margins peeling off. This was caused particularly by liquids such as saliva, food or drinks or by facial expressions. The peeled-off margins led to discomfort and caused the patient to renew the patch. With every replacement, already formed crusts were torn off with the patch, causing pain while promoting primary wound healing. Accompanying symptoms such as pain, tingling, swelling, or burning were also assessed in comparable trials 43, 44. The duration and intensity of symptoms were rated and showed comparable distributions independent of the applied product. This evaluation is important to prove the effective impact of treatment on healing.Chen, F. et al. Efficacy and safety of nucleoside antiviral drugs for treatment of recurrent herpes labialis: a systematic review and meta-analysis. J. Oral Pathol. Med. 46, 561–568 (2017). Besides the film-forming ingredients a number of other substances have been incorporated in Herpatch Cold Sore Serum : Fatahzadeh, M. & Schwartz, R. A. Human herpes simplex virus infections: epidemiology, pathogenesis, symptomatology, diagnosis, and management. J. Am. Acad. Dermatol. 57, 737–763 (2007).

Junker, J. P. E., Kamel, R. A., Caterson, E. J. & Eriksson, E. Clinical Impact Upon Wound Healing and Inflammation in Moist, Wet, and Dry Environments. Adv. Wound Care 2, 348–356 (2013). Spruance, S. L. et al. Early, patient-initiated treatment of herpes labialis with topical 10% acyclovir. Antimicrob. Agents Chemother. 25, 553–555 (1984).

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An alternative is provided in the Compeed Invisible Cold Sore Patches that include no antiviral ingredient (Compeed; Johnson & Johnson Santé Beauté France SAS, Sézanne, France). The cytotoxicity was tested on fibroblasts. Further studies examined the irritation of the patches on rabbits and the sensitivity on guinea pigs. The outer layer of the patch consists of a semiocclusive polyurethane film, which allows excessive wound exudate to evaporate while keeping the lesion moist, ensuring an optimum moisture level. The patch seals the wound and arranges ideal conditions for wound healing. The patch functions as a shield, protecting surrounding areas from infection. As soon as the first symptoms occur, the patch is placed on the lesion, replaced if required, and worn for 24 hours until complete healing occurs 19. Sulfated polysaccharides, which are derived from red microalgae, will create an active protective barrier and as such, will help to protect against sunlight exposure; Having suffered with cold sores since a child I just wanted to say thank you for this incredible treatment I have tried countless other products and this is by far the best I've ever come across. I now keep it permanently in the house and one in the car in case I feel one coming. Again thank you. Skulason, S., Holbrook, W. P., Thormar, H., Gunnarsson, G. B. & Kristmundsdottir, T. A study of the clinical activity of a gel combining monocaprin and doxycycline: a novel treatment for herpes labialis. J. Oral. Pathol. Med. 41, 61–67 (2012).

U.S. Food and Drug Administration. ZOVIRAX (acyclovir) cream 5% for topical use - Reference ID: 3481551 (2014). Gently apply a small amount of serum that will form a film on the cold wound, adequately covering the lesions and a margin of healthy skin around them. After a few minutes, the white serum forms a transparent protective film on the cold wound. If necessary, the serum can be reapplied every 3-4 hours until the cold wound is completely healed. The film can be removed, if necessary, with hot water. The treatment of recurrent HSL turns out to be very difficult and variable. Because of the slight effects of diverse therapies, the infection represents a constant and global public health problem 9. Episodic therapy can be used for relief of accompanying symptoms 10. Therefore, several topical applications, such as phytotherapeuticals, natural remedies, photodynamic therapy, heat and laser application, as well as antiviral substances, can be provided 11, 12, 13, 14, 15, 16.Van Vloten, W. A., Swart, R. N. & Pot, F. Topical acyclovir therapy in patients with recurrent orofacial herpes simplex infections. J. Antimicrob. Chemother. 12, 89–93 (1983). Khemis, A. et al. Evaluation of the efficacy and safety of a CS20 (R) protective barrier gel containing OGT compared with topical aciclovir and placebo on functional and objective symptoms of labial herpes recurrences: a randomized clinical trial. J. Eur. Acad. Dermatol. 26, 1240–1246 (2012).

Naposlijetku, cinkov sulfat smanjuje bol i svrbež, te izaziva stezanje, na koji način učvršćuje, zateže i ojačava kožu. Cinkov suflat će stoga pomoći u ubrzavanju zacjeljivanja bolnih površina izazvanih herpesom. The treatment of recurrent HSL turns out to be very difficult and variable. Because of the slight effects of diverse therapies, the infection represents a constant and global public health problem 9. Episodic therapy can be used for relief of accompanying symptoms 10. Therefore, several topical applications, such as phytotherapeuticals, natural remedies, photodynamic therapy, heat and laser application, as well as antiviral substances, can be provided 11– 16.Petti, S. & Lodi, G. The controversial natural history of oral herpes simplex virus type 1 infection. Oral Dis. 25, 1850–1865 (2019). Raborn, G. W. et al. Effective treatment of herpes simplex labialis with penciclovir cream: combined results of two trials. J. Am. Dent. Assoc. 133, 303–309 (2002). Patora, J. & Klimek, B. Flavonoids from lemon balm (Melissa officinalis L., Lamiaceae). Acta Pol. Pharm. 59, 139–143 (2002).



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